In May, FOX will have a very off-beat crossover event - Agent Booth will suffer a head injury on 'Bones' which will cause him to hallucinate several conversations with Stewie Griffin of 'Family Guy'.
This isn't the Zonk it sounds like. Stewie lives in the Tooniverse and most people in Earth Prime-Time consider such characters to be just "toons". However, these pen-and-ink figures are just as alive as flesh-and-blood characters.
And sometimes they cross over to the actual Toobworld.
The few who know the truth about Toons include Regis Philbin, Kathie Lee Gifford, Jerry Seinfeld, David Letterman, Ryan Seacrest, Drew Carey, Giselle McKenzie, Mimi Bobeck, Lois Lane, and Jimmy Olsen.
(This story was reported by Ausiello of Entertainment Weekly, and his online graphic for his story was so good, I decided to hijack it.)