IM Global is developing a six-hour miniseries about the San Francisco earthquake and fire which nearly devestated the city in '1906' (which will be the title of the project.)
Being set so far in the past, the miniseries shouldn't violate any TV series and the lives of its characters. In fact, the only connection I can see it having would be to the finale of the two-part 'Gambler' TV movie "The Luck Of The Draw", which ended with the first tremors of the earthquake. So I see no reason why this miniseries can't be part of Earth Prime-Time's timeline.
And who knows? Based on its characters' last names, maybe we can conjure a few theories of relateeveety to connect them to residents of modern day San Francisco.....